TNFSF13B
TNFSF13B，即肿瘤坏死因子超家族成员13B，别名BLyS、BAFF、TALL-1。它是一种主要由B细胞产生的细胞因子，属于肿瘤坏死因子超家族成员，在B细胞的成熟和存活中发挥关键作用。TNFSF13B的作用机制涉及与其受体BAFF-R结合，激活下游的信号传导途径，如NF-κB和JAK/STAT通路，促进B细胞的增殖和分化。TNFSF13B在生物学上的意义非常广泛，它参与了B细胞的发育、自身免疫性疾病的发生以及肿瘤的生长。TNFSF13B的异常表达与某些B细胞相关疾病，如系统性红斑狼疮、类风湿关节炎和某些类型的非霍奇金淋巴瘤有关，使其成为治疗这些疾病的潜在靶点。
热销产品
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TNFSF13B Antibody (CSB-PA981923)
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA981923(TNFSF13B Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA981923(TNFSF13B Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: K562 cells, 231 cells, SKOV3 cells, Primary antibody: CSB-PA981923(TNFSF13B Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
TNFSF13B Antibodies
TNFSF13B for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA023990GA01HU | TNFSF13B Antibody | Human | ELISA,WB |
| CSB-PA05767A0Rb | TNFSF13B Antibody | Human | ELISA |
| CSB-PA897523ESR2HU | TNFSF13B Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA005018 | TNFSF13B Antibody | Human,Mouse | WB, ELISA |
| CSB-PA981923 | TNFSF13B Antibody | Human | ELISA,WB,IHC |
| CSB-PA108957 | TNFSF13B Antibody | Human | ELISA,IHC |
TNFSF13B Proteins
TNFSF13B Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP894359MO CSB-EP894359MO CSB-BP894359MO CSB-MP894359MO CSB-EP894359MO-B |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 13B (Tnfsf13b), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TNFSF13B Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP897523HU CSB-BP897523HU CSB-MP897523HU CSB-EP897523HU-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP897523HU | Recombinant Human Tumor necrosis factor ligand superfamily member 13B protein (TNFSF13B), partial | E.coli |
| CSB-AP002191HU | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial (Active) | E.Coli |
| CSB-MP897523HU1 | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial (Active) | Mammalian cell |
| CSB-MP897523HU1-B | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial,Biotinylated (Active) | Mammalian cell |
TNFSF13B ELISA Kit
TNFSF13B ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E11912h | Human B cell activation factor，BAFF ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
