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TGFBR2

TGFBR2,即转化生长因子β受体2,别名TGFβR-II、TGFβRII。它是一种跨膜蛋白,由TGFBR2基因编码,主要在细胞表面发挥作用。TGFBR2的作用机制涉及与转化生长因子β(TGF-β)家族配体结合,激活其内在的丝氨酸/苏氨酸激酶活性,进而磷酸化并激活Smad蛋白,这些Smad蛋白随后转移到细胞核,调控下游基因的表达。TGFBR2在细胞增殖、分化、迁移和凋亡等过程中发挥关键作用,影响组织发育、免疫调节、纤维化和肿瘤发展等生物学过程。

热销产品

Recombinant Human TGF-beta receptor type-2 (TGFBR2), partial (CSB-EP023452HU1)

验证数据

CSB-EP023452HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TGFBR2 Antibody (CSB-PA023452LA01HU)

验证数据

CSB-PA023452LA01HU

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA023452LA01HU at dilution of 1:100

CSB-PA023452LA01HU

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA023452LA01HU at dilution of 1:100

CSB-PA023452LA01HU

Immunofluorescent analysis of MCF-7 cells using CSB-PA023452LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

TGFBR2 Antibodies

TGFBR2 for Homo sapiens (Human)

TGFBR2 Proteins

TGFBR2 Proteins for Rattus norvegicus (Rat)

TGFBR2 Proteins for Sus scrofa (Pig)

TGFBR2 Proteins for Mus musculus (Mouse)

TGFBR2 Proteins for Gallus gallus (Chicken)

TGFBR2 Proteins for Homo sapiens (Human)

TGFBR2 ELISA Kit

TGFBR2 ELISA Kit for Homo sapiens (Human)