PTPN6
PTPN6，全称为蛋白酪氨酸磷酸酶非受体6型，是一种在人体中发挥重要作用的蛋白质。它也被称为HCP、PTP1C、SH-PTP1、Protein-tyrosine phosphatase SHP-1等。PTPN6在细胞信号传导中扮演着关键角色，能够调节多种细胞过程，包括细胞生长、分化、有丝分裂周期和致癌转化。该蛋白与免疫系统的功能密切相关，其异常可能与多种疾病有关，包括癌症和自身免疫疾病。近年来，PTPN6在癌症治疗中的研究引起了广泛关注，它可能成为潜在的生物标志物和治疗靶点。在药物研发方面，针对PTPN6的药物正在被开发，以用于治疗与PTPN6相关的疾病。
热销产品
Recombinant Human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) (CSB-EP019043HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PTPN6 Antibody (CSB-PA019043HA01HU)
验证数据
Western blot
All lanes: PTPN6 antibody at 12µg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: Raji whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 68, 64, 71 kDa
Observed band size: 68 kDa
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA019043HA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA019043HA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA019043HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
PTPN6 Antibodies
PTPN6 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA019043HA01HU | PTPN6 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA019043HB01HU | PTPN6 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA019043HC01HU | PTPN6 Antibody, FITC conjugated | Human | |
| CSB-PA562160 | Phospho-PTPN6 (Tyr536) Antibody | Human,Mouse,Rat | ELISA,IHC,IF |
| CSB-PA561602 | PTPN6 (Ab-536) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA004085 | PTPN6 Antibody | Human | WB, ELISA |
| CSB-PA040102 | Phospho-PTPN6 (Y564) Antibody | Human,Monkey | WB, ELISA |
| CSB-PA040103 | Phospho-PTPN6 (Y536) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040104 | PTPN6 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA282609 | PTPN6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA150036 | PTPN6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
PTPN6 Proteins
PTPN6 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP019043RA CSB-EP019043RA CSB-BP019043RA CSB-MP019043RA CSB-EP019043RA-B |
Recombinant Rat Tyrosine-protein phosphatase non-receptor type 6 (Ptpn6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTPN6 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP019043HU CSB-BP019043HU CSB-MP019043HU CSB-EP019043HU-B |
Recombinant Human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP019043HU | Recombinant Human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) | E.coli |
PTPN6 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP019043MO CSB-BP019043MO CSB-MP019043MO CSB-EP019043MO-B |
Recombinant Mouse Tyrosine-protein phosphatase non-receptor type 6 (Ptpn6) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
