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PTK7

PTK7,即蛋白酪氨酸激酶7,别名CCK4。它是一种由PTK7基因编码的非受体型蛋白酪氨酸激酶,主要在发育和免疫反应中发挥作用。PTK7的作用机制涉及与多种蛋白质相互作用,参与细胞极性、迁移和增殖等过程,特别是在胚胎发育和肿瘤细胞的侵袭中。PTK7参与了细胞内多种信号通路的调控,包括Wnt/PCP和经典Wnt信号通路,影响细胞的极性、运动、迁移和侵袭。此外,PTK7的功能异常与某些疾病有关,如肿瘤的发生和发展。

热销产品

Recombinant Human Inactive tyrosine-protein kinase 7(PTK7),partial (Active) (CSB-MP622651HU2)

验证数据

CSB-MP622651HU2

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP622651HU2

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human PTK7 at 2 μg/ml can bind Anti-PTK7 recombinant antibody (CSB-RA622651MA1HU). The EC50 is 0.3675 - 0.65842 ng/mL.

CSB-MP622651HU2

The purity of PTK7 was greater than 95% as determined by SEC-HPLC

PTK7 Antibody (CSB-PA018996LA01HU)

验证数据

CSB-PA018996LA01HU

IHC image of CSB-PA018996LA01HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Inactive tyrosine-protein kinase 7(PTK7) ELISA kit (CSB-EL018996HU)

验证数据

CSB-EL018996HU 标准曲线

货号:CSB-EL018996HU

规格:96T/48T

灵敏度:3.125 pg/mL

检测范围:12.5 pg/mL-800 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PTK7 Antibodies

PTK7 for Homo sapiens (Human)

PTK7 Proteins

PTK7 Proteins for Homo sapiens (Human)

PTK7 Proteins for Mus musculus (Mouse)

PTK7 Proteins for Gallus gallus (Chicken)

PTK7 ELISA Kit

PTK7 ELISA Kit for Homo sapiens (Human)