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PDGFRB

PDGFRB,即血小板衍生生长因子受体β,别名IBGC4、IMF1、JTK12、PDGF R beta、PDGFR 1。它是一种由PDGFRB基因编码的跨膜受体酪氨酸激酶,主要在多种组织中表达,尤其在肾脏、肺和消化系统中。PDGFRB的作用机制主要是通过与其配体血小板衍生生长因子结合,激活下游的信号传导途径,如PI3K/AKT和RAS/RAF/MEK/ERK等,从而调控细胞的增殖、分化、迁移和存活。PDGFRB在生物学上的意义非常广泛,它参与了多种生理过程的调节,包括血管生成、器官发育和伤口愈合等。PDGFRB的功能异常与多种疾病有关,如某些类型的癌症和血管疾病,因此,它是药物开发和疾病治疗中的一个潜在靶点。

热销产品

Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial (CSB-EP017713HU)

验证数据

CSB-EP017713HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PDGFRB Recombinant Monoclonal Antibody (CSB-RA213932A0HU)

验证数据

CSB-RA213932A0HU

IHC image of CSB-RA213932A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

PDGFRB Antibodies

PDGFRB for Homo sapiens (Human)

PDGFRB Proteins

PDGFRB Proteins for Mus musculus (Mouse)

PDGFRB Proteins for Homo sapiens (Human)

PDGFRB Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)

PDGFRB Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

PDGFRB ELISA Kit

PDGFRB ELISA Kit for Homo sapiens (Human)

PDGFRB ELISA Kit for Mus musculus (Mouse)