PDGFRB
PDGFRB,即血小板衍生生长因子受体β,别名IBGC4、IMF1、JTK12、PDGF R beta、PDGFR 1。它是一种由PDGFRB基因编码的跨膜受体酪氨酸激酶,主要在多种组织中表达,尤其在肾脏、肺和消化系统中。PDGFRB的作用机制主要是通过与其配体血小板衍生生长因子结合,激活下游的信号传导途径,如PI3K/AKT和RAS/RAF/MEK/ERK等,从而调控细胞的增殖、分化、迁移和存活。PDGFRB在生物学上的意义非常广泛,它参与了多种生理过程的调节,包括血管生成、器官发育和伤口愈合等。PDGFRB的功能异常与多种疾病有关,如某些类型的癌症和血管疾病,因此,它是药物开发和疾病治疗中的一个潜在靶点。
热销产品
Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial (CSB-EP017713HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PDGFRB Recombinant Monoclonal Antibody (CSB-RA213932A0HU)
验证数据
IHC image of CSB-RA213932A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
PDGFRB Antibodies
PDGFRB for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA017713GA01HU | PDGFRB Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA828739 | PDGFRB (Ab-751) Antibody | Human,Rat | ELISA,WB |
CSB-PA979025 | Phospho-PDGFRB (Tyr740) Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA556830 | PDGFRB (Ab-771) Antibody | Human,Rat | ELISA,WB |
CSB-PA000745 | Phospho-PDGFRB (Y1021) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA003726 | PDGFRB Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA004625 | PDGFRB Antibody | Human,Rat | WB, ELISA |
CSB-PA030005 | Phospho-PDGFRB (Y771) Antibody | Human,Rat | WB, ELISA |
CSB-PA030006 | Phospho-PDGFRB (Y740) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA030007 | Phospho-PDGFRB (Y751) Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
CSB-PA030008 | PDGFRB Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
CSB-PA030009 | PDGFRB Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA030010 | PDGFRB Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA208206 | PDGFRB Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA266610 | PDGFRB Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA017713LA01HU | PDGFRB Antibody | Human | ELISA, IHC, IF |
CSB-PA017713LD01HU | PDGFRB Antibody, Biotin conjugated | Human | ELISA |
CSB-PA017713LC01HU | PDGFRB Antibody, FITC conjugated | Human | |
CSB-PA017713LB01HU | PDGFRB Antibody, HRP conjugated | Human | ELISA |
CSB-RA017713A740phHU | Phospho-PDGFRB (Y740) Recombinant Monoclonal Antibody | Human | ELISA, WB |
CSB-RA213932A0HU | PDGFRB Recombinant Monoclonal Antibody | Human | ELISA, IHC |
PDGFRB Proteins
PDGFRB Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP017713MO CSB-EP017713MO CSB-BP017713MO CSB-MP017713MO CSB-EP017713MO-B |
Recombinant Mouse Platelet-derived growth factor receptor beta (Pdgfrb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDGFRB Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP017713HU CSB-BP017713HU CSB-MP017713HU CSB-EP017713HU-B |
Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP017713HU | Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial | E.coli |
PDGFRB Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP304446TKY CSB-EP304446TKY CSB-BP304446TKY CSB-MP304446TKY CSB-EP304446TKY-B |
Recombinant Takifugu rubripes Platelet-derived growth factor receptor beta (pdgfrb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDGFRB Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP764838DO CSB-EP764838DO CSB-BP764838DO CSB-MP764838DO CSB-EP764838DO-B |
Recombinant Dog Platelet-derived growth factor receptor beta (PDGFRB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDGFRB ELISA Kit
PDGFRB ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL017713HU | Human Beta-type platelet-derived growth factor receptor(PDGFRB) ELISA kit | serum, plasma, tissue homogenates | 15.6 pg/mL |
PDGFRB ELISA Kit for Mus musculus (Mouse)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL017713MO | Mouse Beta-type platelet-derived growth factor receptor(PDGFRB) ELISA kit |