NECTIN2
NECTIN2，也称为nectin cell adhesion molecule 2，是一种细胞粘附分子，属于免疫球蛋白超家族。它主要在细胞间粘附和紧密连接的形成与维持中发挥作用。NECTIN2在T细胞信号传导中具有双重作用，既能作为CD226的共刺激剂促进增殖和细胞因子产生，也能作为PVRIG的共抑制剂抑制增殖。此外，它还充当细胞粘附蛋白和某些病毒的受体。与NECTIN2相关的疾病包括多发性硬化症等。在药物研发方面，针对NECTIN2的药物主要针对癌症治疗，目前已有多个靶向NECTIN2的药物处于研发阶段。
热销产品
NECTIN2 Antibody (CSB-PA835690LA01HU)
验证数据
Western Blot
Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate, Hela whole cell lysate
All lanes: NECTIN2 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 58, 52 kDa
Observed band size: 58 kDa
NECTIN2 Antibodies
NECTIN2 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA019096GA01HU | PVRL2 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA006259 | PVRL2 Antibody | Human | WB, ELISA |
| CSB-PA163325 | PVRL2 Antibody | Human | ELISA,IHC |
| CSB-PA835690LA01HU | NECTIN2 Antibody | Human | ELISA, WB |
| CSB-PA835690LB01HU | NECTIN2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA835690LC01HU | NECTIN2 Antibody, FITC conjugated | Human |
NECTIN2 Proteins
NECTIN2 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP019096MO1 CSB-EP019096MO1 CSB-BP019096MO1 CSB-MP019096MO1 CSB-EP019096MO1-B |
Recombinant Mouse Poliovirus receptor-related protein 2 (Pvrl2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF019096MO | Recombinant Mouse Nectin-2 (Nectin2) | in vitro E.coli expression system |
NECTIN2 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP835690HU CSB-BP835690HU CSB-MP835690HU CSB-EP835690HU-B |
Recombinant Human Poliovirus receptor-related protein 2 (PVRL2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP835690HU | Recombinant Human Nectin-2 (PVRL2), partial | E.coli |
| CSB-AP005081HU | Recombinant Human Nectin-2 (NECTIN2), partial (Active) | Mammalian cell |
