KMT2A
KMT2A，即赖氨酸特异性组蛋白甲基转移酶2A，别名MLL1、HYPB、TRXR1。它是一种由KMT2A基因编码的酶，属于非典型组蛋白甲基转移酶家族成员。KMT2A的作用机制是通过催化组蛋白H3第4位赖氨酸的二甲基化（H3K4me2），参与调控基因的表达，特别是在细胞分化和发育过程中。KMT2A在细胞增殖、神经发育、造血和肿瘤发生等生物学过程中具有重要作用。其功能异常与遗传性疾病和癌症的发生发展有关，是药物开发和疾病治疗中的潜在靶点。
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验证数据
Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
KMT2A Antibodies
KMT2A for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA612015 | KMT2A Antibody | Human,Mouse,Rat | IHC,ELISA |
KMT2A Proteins
KMT2A Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP014627MO CSB-EP014627MO CSB-BP014627MO CSB-MP014627MO CSB-EP014627MO-B |
Recombinant Mouse Histone-lysine N-methyltransferase MLL (Mll), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
