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IL7R

IL7R,即白细胞介素7受体,别名CD127。它是一种由IL7R基因编码的蛋白质,属于I型细胞因子受体家族,在多种免疫细胞表面表达,包括T细胞、B细胞和自然杀伤(NK)细胞。IL7R的作用机制涉及与其配体IL-7结合,激活JAK/STAT信号通路,促进免疫细胞的增殖、存活和分化。IL7R参与了免疫系统的发育和维持,特别是对T细胞亚群的调节作用。IL7R的表达水平在某些疾病中发生变化,如免疫缺陷病、癌症和慢性感染,是免疫学研究和相关疾病治疗中的一个潜在靶点。

热销产品

Recombinant Human Interleukin-7 receptor subunit alpha (IL7R), partial (CSB-EP011670HU1)

验证数据

CSB-EP011670HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

IL7R Antibody (CSB-PA011670ESR1HU)

验证数据

CSB-PA011670ESR1HU

Western blot
All lanes: IL7R antibody at 4µg/ml
Lane 1: K562 whole cell lysate
Lane 2: Jurkat whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 52, 35, 30, 29 kDa
Observed band size: 52 kDa  

CSB-PA011670ESR1HU

Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA011670ESR1HU at dilution of 1:100

CSB-PA011670ESR1HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA011670ESR1HU at dilution of 1:100

IL7R Antibodies

IL7R for Homo sapiens (Human)

IL7R Proteins

IL7R Proteins for Homo sapiens (Human)

IL7R Proteins for Mus musculus (Mouse)

IL7R Proteins for Equus caballus (Horse)

IL7R Proteins for Callithrix jacchus (White-tufted-ear marmoset)

IL7R Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

IL7R ELISA Kit

IL7R ELISA Kit for Homo sapiens (Human)

IL7R ELISA Kit for Mus musculus (Mouse)