IL2RB
白细胞介素-2受体β链（IL-2RB）又称CD122，是免疫调节中的关键膜蛋白。该分子通过与γ链共同构成功能性受体复合物，在激活T细胞和自然杀伤细胞中发挥核心作用。IL2RB功能异常与多种免疫疾病密切相关，例如系统性红斑狼疮患者常出现该受体信号传导紊乱，而霍奇金淋巴瘤等血液肿瘤中则存在受体过度激活现象。临床上已有针对IL-2受体的人源化单抗药物，如巴利昔单抗被用于预防肾移植排斥反应。近年研究聚焦于开发选择性调节剂，利用该受体在调节性T细胞与效应T细胞中的差异化表达特征，旨在实现更精准的免疫平衡控制。在肿瘤免疫治疗领域，部分处于Ⅱ期临床试验的双特异性抗体通过靶向CD122增强抗肿瘤免疫应答，为实体瘤治疗提供了新思路。
热销产品
验证数据
Western blot analysis on HeLa cell lysate using IL-2Rbeta/CD122 antibody,The lane on the left is treated with the antigen-specific peptide.
IL2RB Antibodies
IL2RB for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA011650GA01HU | IL2RB Antibody | Human | ELISA,WB |
| CSB-PA081831 | IL2RB Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA163341 | Phospho-IL2RB (Tyr364) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA832482 | IL2RB (Ab-364) Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA009546 | Phospho-IL2RB (Y364) Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA009547 | Phospho-IL2RB (Y364) Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA009548 | IL2RB Antibody | Human | WB, ELISA |
| CSB-PA009549 | IL2RB Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA009550 | IL2RB Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA061951 | IL2RB Antibody | Human | ELISA,WB,IHC |
| CSB-PA114100 | IL2RB Antibody | Human | ELISA,WB,IHC |
IL2RB for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA011650LB01MO | Il2rb Antibody, HRP conjugated | Mouse | ELISA |
| CSB-PA011650LA01MO | Il2rb Antibody | Mouse | ELISA |
| CSB-PA011650LC01MO | Il2rb Antibody, FITC conjugated | Mouse |
IL2RB Proteins
IL2RB Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011650HU1 CSB-EP011650HU1 CSB-BP011650HU1 CSB-MP011650HU1 CSB-EP011650HU1-B |
Recombinant Human Interleukin-2 receptor subunit beta (IL2RB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011650HU | Recombinant Human Interleukin-2 receptor subunit beta (IL2RB) | in vitro E.coli expression system |
IL2RB Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011650MO | Recombinant Mouse Interleukin-2 receptor subunit beta (Il2rb), partial | Yeast |
| CSB-EP011650MO1 | Recombinant Mouse Interleukin-2 receptor subunit beta (Il2rb), partial | E.coli |
IL2RB Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011650RA1 CSB-EP011650RA1 CSB-BP011650RA1 CSB-EP011650RA1-B |
Recombinant Rat Interleukin-2 receptor subunit beta (Il2rb), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF011650RA | Recombinant Rat Interleukin-2 receptor subunit beta (Il2rb) | in vitro E.coli expression system |
IL2RB Proteins for Pan troglodytes (Chimpanzee)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP654343EQV CSB-EP654343EQV CSB-BP654343EQV CSB-MP654343EQV CSB-EP654343EQV-B |
Recombinant Pan troglodytes Interleukin-2 receptor subunit beta (IL2RB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL2RB Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP657828MOV CSB-BP657828MOV CSB-EP657828MOV-B |
Recombinant Macaca fascicularis Interleukin-2 receptor subunit beta (IL2RB), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP657828MOV | Recombinant Macaca fascicularis Interleukin-2 receptor subunit beta (IL2RB), partial | E.coli |
