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IL17A

IL17A,即白细胞介素17A。别名CTLA8。它主要由活化的T细胞产生,尤其是Th17细胞,CD8+ T细胞、γδT细胞、自然杀伤T细胞(NKT)、单核细胞和中性粒细胞也能产生IL-17A。IL-17A的作用机制涉及与IL-17受体家族结合,特别是与IL-17RA以高亲和力结合,激活下游信号通路,促进炎症因子的产生。IL-17A在宿主防御多种细菌和真菌病原体中发挥关键作用,同时也参与过敏和自身免疫反应。它诱导抗菌肽、细胞因子、趋化因子和基质金属蛋白酶的产生,参与炎症和组织修复过程,与多种自身免疫性疾病和肿瘤的发生发展相关。

热销产品

Recombinant Human Interleukin-17A (IL17A) (T26A) (Active) (CSB-BP624104HU(M))

验证数据

CSB-BP624104HU(M)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-BP624104HU(M)

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL17A at 2 μg/ml can bind Anti-IL17A recombinant antibody (CSB-RA624104MA1HU), the EC50 is 1.818-2.170 ng/mL.

IL17A Recombinant Monoclonal Antibody (CSB-RA624104MA1HU)

验证数据

CSB-RA624104MA1HU

The Binding Activity of IL17A with anti-IL17A antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL17A(CSB-BP624104HU(M)) at 2 μg/ml can bind Anti-IL17A recombinant antibody, the EC50 is 1.818-2.170 ng/mL.

IL17A Antibodies

IL17A for Homo sapiens (Human)

IL17A Proteins

IL17A Proteins for Homo sapiens (Human)

IL17A Proteins for Rattus norvegicus (Rat)

IL17A Proteins for Mus musculus (Mouse)

IL17A Proteins for Bos taurus (Bovine)

IL17A Proteins for Sus scrofa (Pig)

IL17A ELISA Kit

IL17A ELISA Kit for Mus musculus (Mouse)

IL17A ELISA Kit for Sus scrofa (Pig)

IL17A ELISA Kit for Rattus norvegicus (Rat)

IL17A ELISA Kit for Homo sapiens (Human)