IL17A
IL17A,即白细胞介素17A。别名CTLA8。它主要由活化的T细胞产生,尤其是Th17细胞,CD8+ T细胞、γδT细胞、自然杀伤T细胞(NKT)、单核细胞和中性粒细胞也能产生IL-17A。IL-17A的作用机制涉及与IL-17受体家族结合,特别是与IL-17RA以高亲和力结合,激活下游信号通路,促进炎症因子的产生。IL-17A在宿主防御多种细菌和真菌病原体中发挥关键作用,同时也参与过敏和自身免疫反应。它诱导抗菌肽、细胞因子、趋化因子和基质金属蛋白酶的产生,参与炎症和组织修复过程,与多种自身免疫性疾病和肿瘤的发生发展相关。
热销产品
Recombinant Human Interleukin-17A (IL17A) (T26A) (Active) (CSB-BP624104HU(M))
验证数据
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL17A at 2 μg/ml can bind Anti-IL17A recombinant antibody (CSB-RA624104MA1HU), the EC50 is 1.818-2.170 ng/mL.
IL17A Recombinant Monoclonal Antibody (CSB-RA624104MA1HU)
验证数据

The Binding Activity of IL17A with anti-IL17A antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL17A(CSB-BP624104HU(M)) at 2 μg/ml can bind Anti-IL17A recombinant antibody, the EC50 is 1.818-2.170 ng/mL.
IL17A Antibodies
IL17A for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA011597GA01HU | IL17A Antibody | Human | ELISA,IHC |
CSB-PA06659A0Rb | IL17A Antibody | Human | ELISA, IHC, IF |
CSB-PA06659B0Rb | IL17A Antibody, HRP conjugated | Human | ELISA |
CSB-PA06659C0Rb | IL17A Antibody, FITC conjugated | Human | |
CSB-PA06659D0Rb | IL17A Antibody, Biotin conjugated | Human | ELISA |
CSB-RA624104MA1HU | IL17A Recombinant Monoclonal Antibody | Human | ELISA |
IL17A Proteins
IL17A Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP624104HU CSB-EP624104HU CSB-BP624104HU CSB-MP624104HU CSB-EP624104HU-B |
Recombinant Human Interleukin-17A (IL17A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP001851HU | Recombinant Human Interleukin-17A protein (IL17A) | E.Coli |
CSB-AP004331HU | Recombinant Human Interleukin-17A (IL17A) (Active) | E.coli |
CSB-AP004341HU | Recombinant Human Interleukin-17A (IL17A) (Active) | Mammalian cell |
CSB-AP004701HU | Recombinant Human IL17A & IL17F Heterodimer Protein (Active) | Mammalian cell |
CSB-EP624104HU1 | Recombinant Human Interleukin-17A (IL17A), partial | E.coli |
CSB-BP624104HU(M) | Recombinant Human Interleukin-17A (IL17A) (T26A) (Active) | Baculovirus |
IL17A Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP717213RA CSB-BP717213RA CSB-MP717213RA CSB-EP717213RA-B |
Recombinant Rat Interleukin-17A (Il17a) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17A Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP720298MO CSB-EP720298MO CSB-BP720298MO CSB-MP720298MO CSB-EP720298MO-B |
Recombinant Mouse Interleukin-17A (Il17a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP004781MO | Recombinant Mouse Interleukin-17A (Il17a), partial (Active) | Mammalian cell |
IL17A Proteins for Bos taurus (Bovine)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP724243BO CSB-BP724243BO CSB-MP724243BO CSB-EP724243BO-B |
Recombinant Bovine Interleukin-17A (IL17A) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17A Proteins for Sus scrofa (Pig)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP736792PI CSB-BP736792PI CSB-MP736792PI CSB-EP736792PI-B |
Recombinant Pig Interleukin-17A (IL17A) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17A ELISA Kit
IL17A ELISA Kit for Mus musculus (Mouse)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E04608m | Mouse Interleukin 17,IL-17 ELISA Kit | serum, plasma, tissue homogenates | 19.5 pg/ml |
IL17A ELISA Kit for Sus scrofa (Pig)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E08057p | Pig interleukin 17,IL-17 ELISA Kit | serum, plasma, tissue homogenates | 10 pg/mL |
IL17A ELISA Kit for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E07451r | Rat Interleukin 17,IL-17 ELISA KIT | serum, plasma, tissue homogenates | 23.43 pg/mL |
IL17A ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E12819h | Human Interleukin 17A (IL-17A/IL-17) ELISA Kit | serum, plasma, tissue homogenates | 15.6 pg/ml |
CSB-E12819h-IS | Human Interleukin 17A (IL-17A/IL-17) ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 3.9 pg/ml |