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IL13RA1

IL13RA1,即白细胞介素13受体亚单位α1,别名NR4、CT19、CD213A1。它是由人类IL13RA1基因编码的蛋白质,该基因位于X染色体上。IL13RA1是IL-13受体的主要结合亚基,与IL-4受体α形成受体复合体,这是IL-13和IL-4受体共有的亚基。IL13RA1与IL-13结合后,与IL-4受体α链形成异二聚体,激活JAK2/Tyk2依赖的信号转导和转录激活因子STAT的磷酸化。IL13RA1在免疫调节、炎症反应、过敏反应等多个生物学过程中发挥关键作用,对单核巨噬细胞、B淋巴细胞、NK细胞和血管内皮细胞等具有多种生物学作用,是机体免疫反应的重要调节介质。

热销产品

Recombinant Human Interleukin-13 receptor subunit alpha-1 (IL13RA1) (CSB-CF011591HU)

验证数据

CSB-CF011591HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

IL13RA1 Recombinant Monoclonal Antibody (CSB-RA011591MA1HU)

验证数据

CSB-RA011591MA1HU

IHC image of CSB-RA011591MA1HU diluted at 1:200 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.

IL13RA1 Antibodies

IL13RA1 for Homo sapiens (Human)

IL13RA1 Proteins

IL13RA1 Proteins for Homo sapiens (Human)

IL13RA1 Proteins for Mus musculus (Mouse)