Your Good Partner in Biology Research

GIPR

GIPR,即胃抑制多肽受体,别名PGQTL2。GIPR由人类GIPR基因编码,该基因位于19号染色体的q13.32区域。GIPR是一种G蛋白偶联受体,其内源性配体为葡萄糖依赖性促胰岛素释放多肽(GIP),在脂肪生成、胰岛β细胞增殖和胰岛素释放等方面发挥重要作用,与2型糖尿病、肥胖症和神经退行性疾病相关。
GIPR与GIP结合后可激活腺苷酸环化酶-环磷酸腺苷-蛋白激酶A通路,促进胰岛素分泌。GIPR在调节餐后血糖浓度中起到关键作用,在高血糖条件下促进胰岛素的分泌;在低血糖条件下刺激胰岛α细胞释放胰高血糖素,从而维持血糖稳态。GIPR的异常表达或功能失调可能与糖尿病的发病机制相关,是糖尿病治疗的潜在靶点。

热销产品

Recombinant Macaca fascicularis Gastric inhibitory polypeptide receptor (GIPR), partial (Active) (CSB-YP4825MOV)

验证数据

CSB-YP4825MOV

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-YP4825MOV

Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis GIPR at 2μg/mL can bind Anti-GIPR recombinant antibody (CSB-RA009438MA1HU),the EC50 is 12.66-13.86 ng/mL.

Recombinant Rat Gastric inhibitory polypeptide receptor (Gipr), partial (Active) (CSB-MP009438RA1)

验证数据

CSB-MP009438RA1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP009438RA1

Activity
Measured by its binding ability in a functional ELISA. Immobilized Rat Gipr at 2μg/mL can bind Anti-Mouse Gipr recombinant antibody (CSB-RA009438MA1MO), the EC50 is 6.946-8.740 ng/mL.

Recombinant Mouse Gastric inhibitory polypeptide receptor (Gipr), partial (Active) (CSB-MP009438MO1)

验证数据

CSB-MP009438MO1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP009438MO1

Activity
Measured by its binding ability in a functional ELISA. Immobilized Mouse Gipr at 2μg/mL can bind Anti-Mouse Gipr recombinant antibody (CSB-RA009438MA1MO), the EC50 is 8.622-11.36 ng/mL.

Recombinant Human Gastric inhibitory polypeptide receptor(GIPR),partial (Active) (CSB-MP009438HU1d7)

验证数据

CSB-MP009438HU1d7

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP009438HU1d7

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human GIPR at 2μg/mL can bind Anti-GIPR recombinant antibody (CSB-RA009438MA1HU),the EC50 is 16.18-18.70 ng/mL.

CSB-MP009438HU1d7

The purity of GIPR was greater than 95% as determined by SEC-HPLC

GIPR Recombinant Monoclonal Antibody (CSB-RA009438MA1HU)

验证数据

CSB-RA009438MA1HU

The Binding Activity of Macaca fascicularis GIPR with Anti-GIPR recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis GIPR (CSB-YP4825MOV) at 2 μg/mL can bind Anti-GIPR recombinant antibody. The EC50 is 12.66-13.86 ng/mL.

CSB-RA009438MA1HU

The Binding Activity of Human GIPR with Anti-GIPR recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GIPR (CSB-MP009438HU1d7) at 2 μg/mL can bind Anti-GIPR recombinant antibody. The EC50 is 16.18-18.70 ng/mL.

GIPR Antibodies

GIPR for Homo sapiens (Human)

GIPR for Mus musculus (Mouse)

GIPR Proteins

GIPR Proteins for Rattus norvegicus (Rat)

GIPR Proteins for Homo sapiens (Human)

GIPR Proteins for Mesocricetus auratus (Golden hamster)

GIPR Proteins for Mus musculus (Mouse)

GIPR Proteins for Mus musculus (Mouse)