DLL4
DLL4，全称为Delta-like protein 4。它在Notch信号通路中扮演重要角色，作为Notch配体激活NOTCH1和NOTCH4，参与细胞通信和血管生成调控。DLL4蛋白与多种疾病相关，如上皮性卵巢癌等。在药物研发方面，DLL4蛋白已成为抗肿瘤治疗的新靶点，相关双抗药物如VEGF/DLL4双抗在临床试验中取得显著进展，有望成为胆道癌二线治疗的新标准。
热销产品
Recombinant Human Delta-like protein 4 (DLL4),partial (Active) (CSB-MP878862HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human DLL4 at 2 μg/ml can bind Anti-DLL4 recombinant antibody (CSB-RA878862MA1HU). The EC50 is 2.322-2.607 ng/mL.
DLL4 Recombinant Monoclonal Antibody (CSB-RA878862MA1HU)
验证数据
The Binding Activity of Human DLL4 with Anti-DLL4 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DLL4 (CSB-MP878862HU) at 2 μg/mL can bind Anti-DLL4 recombinant antibody . The EC50 is 2.322-2.607 ng/mL.
DLL4 Antibodies
DLL4 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA073786 | DLL4 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA831848 | DLL4 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA006949LA01HU | DLL4 Antibody | Human | ELISA, IF |
| CSB-PA006949LB01HU | DLL4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA006949LC01HU | DLL4 Antibody, FITC conjugated | Human | |
| CSB-PA006949LD01HU | DLL4 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA878862MA1HU | DLL4 Recombinant Monoclonal Antibody | Human | ELISA |
DLL4 Proteins
DLL4 Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP347231XBE CSB-EP347231XBE CSB-BP347231XBE CSB-MP347231XBE CSB-EP347231XBE-B |
Recombinant Xenopus laevis Homeobox protein DLL-4 (dll4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DLL4 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP867483MO CSB-EP867483MO CSB-BP867483MO CSB-MP867483MO CSB-EP867483MO-B |
Recombinant Mouse Delta-like protein 4 (Dll4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DLL4 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP878862HU CSB-EP878862HU CSB-BP878862HU CSB-EP878862HU-B |
Recombinant Human Delta-like protein 4 (DLL4), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP878862HU | Recombinant Human Delta-like protein 4 (DLL4),partial (Active) | Mammalian cell |
DLL4 ELISA Kit
DLL4 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL006949HU | Human Delta-like protein 4(DLL4) ELISA kit | serum, plasma, tissue homogenates | 5.8 pg/mL |
DLL4 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL006949MO | Mouse Delta-like protein 4(DLL4) ELISA kit | serum, plasma, tissue homogenates | 0.04 ng/mL |
