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DLL4

DLL4,全称为Delta-like protein 4。它在Notch信号通路中扮演重要角色,作为Notch配体激活NOTCH1和NOTCH4,参与细胞通信和血管生成调控。DLL4蛋白与多种疾病相关,如上皮性卵巢癌等。在药物研发方面,DLL4蛋白已成为抗肿瘤治疗的新靶点,相关双抗药物如VEGF/DLL4双抗在临床试验中取得显著进展,有望成为胆道癌二线治疗的新标准。

热销产品

Recombinant Human Delta-like protein 4 (DLL4),partial (Active) (CSB-MP878862HU)

验证数据

CSB-MP878862HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP878862HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human DLL4 at 2 μg/ml can bind Anti-DLL4 recombinant antibody (CSB-RA878862MA1HU). The EC50 is 2.322-2.607 ng/mL.

DLL4 Recombinant Monoclonal Antibody (CSB-RA878862MA1HU)

验证数据

CSB-RA878862MA1HU

The Binding Activity of Human DLL4 with Anti-DLL4 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DLL4 (CSB-MP878862HU) at 2 μg/mL can bind Anti-DLL4 recombinant antibody . The EC50 is 2.322-2.607 ng/mL.

DLL4 Antibodies

DLL4 for Homo sapiens (Human)

DLL4 Proteins

DLL4 Proteins for Xenopus laevis (African clawed frog)

DLL4 Proteins for Mus musculus (Mouse)

DLL4 Proteins for Homo sapiens (Human)

DLL4 ELISA Kit

DLL4 ELISA Kit for Homo sapiens (Human)

DLL4 ELISA Kit for Mus musculus (Mouse)