CREBBP
CREBBP，即cAMP反应元件结合蛋白结合蛋白，别名CBP、RSTS、KAT3A、MKHK1、RSTS1。CREBBP是一种在细胞核中广泛表达的基因，它通过与多种转录因子相互作用，参与胚胎发育、生长控制和体内平衡等重要生理过程。CREBBP的作用机制主要体现在其编码的蛋白质上，该蛋白质具有组蛋白乙酰转移酶活性，能够乙酰化组蛋白和非组蛋白，从而调控基因的转录。此外，CREBBP蛋白还作为支架蛋白，稳定与其他蛋白质的相互作用，促进转录复合物的形成。CREBBP对维持细胞的正常功能和调控细胞周期具有重要作用。CREBBP基因的突变可导致Rubinstein-Taybi综合征（RTS），并且与急性髓性白血病的发生有关。
热销产品
Recombinant Human CREB-binding protein (CREBBP), partial (CSB-EP838805HU1)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CREBBP Antibody (CSB-PA838805LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA838805LA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA838805LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
CREBBP Antibodies
CREBBP for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA901849 | CREBBP Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA000107 | Acetyl-CREBBP (K1535) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA001358 | CREBBP Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA001359 | CREBBP Antibody | Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA824713 | CREBBP Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA838805LA01HU | CREBBP Antibody | Human | ELISA, IHC, IF |
CREBBP Proteins
CREBBP Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP005954MO CSB-EP005954MO CSB-BP005954MO CSB-MP005954MO CSB-EP005954MO-B |
Recombinant Mouse CREB-binding protein (Crebbp), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CREBBP Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP757128RA CSB-EP757128RA CSB-BP757128RA CSB-MP757128RA CSB-EP757128RA-B |
Recombinant Rat CREB-binding protein (Crebbp), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CREBBP Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP838805HU CSB-EP838805HU CSB-BP838805HU CSB-MP838805HU CSB-EP838805HU-B |
Recombinant Human CREB-binding protein (CREBBP), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP838805HU1 | Recombinant Human CREB-binding protein (CREBBP), partial | E.coli |
