CD79A
CD79A，即B细胞抗原受体复合体α链，别名MB-1、IGA、Ig-alpha、IGAB、CD79amolecule。它是一种47kDa的膜糖蛋白，与CD79B结合形成异二聚体B细胞受体(BCR)，这种受体负责B细胞信号传导，导致激活、凋亡或过敏。CD79A的作用机制主要是与CD79B共同参与B细胞受体的信号转导。当抗原与BCR结合后，CD79A/CD79B异二聚体能够传递激活信号，引发B细胞的增殖、分化和抗体产生。CD79A的细胞质区含有免疫受体酪氨酸激活基序(ITAM)，是信号转导的关键结构。CD79A对B细胞功能的重要调控作用，参与B细胞的抗原识别、激活、增殖和分化等过程。CD79A的表达还与某些B细胞肿瘤的发生发展相关，如B细胞急性淋巴细胞性白血病(B-ALL)等。CD79A是B细胞生物学研究和B细胞相关疾病治疗的重要靶点。
热销产品
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CD79A at 2 μg/ml can bind Anti-CD79A recombinant antibody(CSB-RA004957MA1HU). The EC50 is 1.521-1.700 ng/mL.
CD79A Recombinant Monoclonal Antibody (CSB-RA004957MA1HU)
验证数据
The Binding Activity of Human CD79A with Anti-CD79A recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD79A(CSB-MP004957HU1) at 2 μg/mL can bind Anti-CD79A recombinant antibody. The EC50 is 1.521-1.700 ng/mL.
The Binding Activity of Human CD79A&CD79B with Anti-CD79A recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD79A&CD79B(CSB-MP5861HU) at 2 μg/mL can bind Anti-CD79A recombinant antibody. The EC50 is 8.012-9.339 ng/mL.
The purity of CD79A was greater than 95% as determined by SEC-HPLC
CD79A Antibodies
CD79A for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA165334 | CD79A Antibody | Human | ELISA,WB |
| CSB-PA080055 | CD79A Antibody | Human | WB, ELISA |
| CSB-PA080056 | CD79A Antibody | Human,Mouse | WB, ELISA |
| CSB-PA780889 | CD79A Antibody | Human,Mouse | ELISA,WB |
| CSB-PA183306 | CD79A Antibody | Human,Mouse | ELISA,WB |
| CSB-PA004957LA01HU | CD79A Antibody | Human | ELISA, IHC, IF |
| CSB-PA004957LB01HU | CD79A Antibody, HRP conjugated | Human | ELISA |
| CSB-PA004957LC01HU | CD79A Antibody, FITC conjugated | Human | |
| CSB-MA961575 | CD79A Monoclonal Antibody | Human | ELISA, IHC |
| CSB-RA004957MA1HU | CD79A Recombinant Monoclonal Antibody | Human | ELISA |
CD79A Proteins
CD79A Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004957DO1 CSB-EP004957DO1 CSB-BP004957DO1 CSB-MP004957DO1 CSB-EP004957DO1-B |
Recombinant Dog B-cell antigen receptor complex-associated protein alpha chain (CD79A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004957DO | Recombinant Dog B-cell antigen receptor complex-associated protein alpha chain (CD79A) | in vitro E.coli expression system |
CD79A Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004957MO1 CSB-EP004957MO1 CSB-BP004957MO1 CSB-MP004957MO1 CSB-EP004957MO1-B |
Recombinant Mouse B-cell antigen receptor complex-associated protein alpha chain (Cd79a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004957MO | Recombinant Mouse B-cell antigen receptor complex-associated protein alpha chain (Cd79a) | in vitro E.coli expression system |
CD79A Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004957HU1 CSB-EP004957HU1 CSB-BP004957HU1 CSB-EP004957HU1-B |
Recombinant Human B-cell antigen receptor complex-associated protein alpha chain (CD79A), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF004957HU | Recombinant Human B-cell antigen receptor complex-associated protein alpha chain (CD79A) | in vitro E.coli expression system |
| CSB-MP004957HU1 | Recombinant Human B-cell antigen receptor complex-associated protein alpha chain (CD79A）, partial (Active) | Mammalian cell |
CD79A Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004957BO1 CSB-EP004957BO1 CSB-BP004957BO1 CSB-MP004957BO1 CSB-EP004957BO1-B |
Recombinant Bovine B-cell antigen receptor complex-associated protein alpha chain (CD79A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004957BO | Recombinant Bovine B-cell antigen receptor complex-associated protein alpha chain (CD79A) | in vitro E.coli expression system |
