BRCA1
BRCA1，即乳腺癌易感基因1，别名FANCS、PSCP。它是由人类BRCA1基因编码的，该基因位于17号染色体的q21位置。BRCA1是一种核磷蛋白，作为肿瘤抑制因子发挥作用，参与多种细胞过程，包括转录、DNA双链断裂的修复和重组。BRCA1的作用机制涉及与多种蛋白质相互作用，形成BRCA1相关基因组监测复合物（BASC），参与DNA损伤修复和细胞周期调控。BRCA1-BARD1异二聚体表现出E3Ub连接酶活性，参与DNA末端切除和DNA保护。BRCA1对维持基因组稳定性至关重要，其突变可导致遗传性乳腺癌和卵巢癌，影响约40%的遗传性乳腺癌和80%以上的遗传性乳腺癌和卵巢癌。
热销产品
验证数据
Western Blot analysis of 293 cells using BRCA1 Polyclonal Antibody
Western Blot analysis of 823 293-UV 22RV1 cells using BRCA1 Polyclonal Antibody
BRCA1 Antibodies
BRCA1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA09659A0Rb | BRCA1 Antibody | Human | ELISA |
| CSB-PA09659B0Rb | BRCA1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA09659D0Rb | BRCA1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA002794GA01HU | BRCA1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA596474 | Phospho-BRCA1 (Ser1524) Antibody | Human | ELISA,IHC |
| CSB-PA234605 | Phospho-BRCA1 (Ser1423) Antibody | Human | ELISA,WB,IHC |
| CSB-PA904513 | BRCA1 (Ab-1524) Antibody | Human | ELISA,WB,IF |
| CSB-PA186422 | BRCA1 (Ab-1423) Antibody | Human | ELISA,WB,IHC |
| CSB-PA901818 | Phospho-BRCA1 (Ser988) Antibody | Human | ELISA,IF |
| CSB-PA258596 | Phospho-BRCA1 (Ser1457) Antibody | Human | ELISA,WB |
| CSB-PA001041 | BRCA1 Antibody | Human | WB, IHC, ELISA |
| CSB-PA001042 | BRCA1 Antibody | Human,Rat | WB, IHC, IF, ELISA |
| CSB-PA050135 | Phospho-BRCA1 (S1423) Antibody | Human,Rat | WB, IHC, ELISA |
| CSB-PA050136 | Phospho-BRCA1 (S1524) Antibody | Human | IHC, ELISA |
| CSB-PA050137 | Phospho-BRCA1 (S1457) Antibody | Human | WB, ELISA |
| CSB-PA050138 | BRCA1 Antibody | Human | WB, ELISA |
| CSB-PA050139 | BRCA1 Antibody | Human | IHC, ELISA |
| CSB-PA291937 | BRCA1 Antibody | Human | ELISA,IHC |
| CSB-PA678542 | BRCA1 Antibody | Human | ELISA,IHC |
BRCA1 Proteins
BRCA1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002794HU CSB-EP002794HU CSB-BP002794HU CSB-MP002794HU CSB-EP002794HU-B |
Recombinant Human Breast cancer type 1 susceptibility protein (BRCA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP096594h(N) | Recombinant Human Breast cancer type 1 susceptibility protein (BRCA1), partial | E.coli |
BRCA1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP344548MO CSB-EP344548MO CSB-BP344548MO CSB-MP344548MO CSB-EP344548MO-B |
Recombinant Mouse Breast cancer type 1 susceptibility protein homolog (Brca1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRCA1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP526320RA CSB-EP526320RA CSB-BP526320RA CSB-MP526320RA CSB-EP526320RA-B |
Recombinant Rat Breast cancer type 1 susceptibility protein homolog (Brca1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRCA1 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP740265MOW CSB-EP740265MOW CSB-BP740265MOW CSB-MP740265MOW CSB-EP740265MOW-B |
Recombinant Macaca mulatta Breast cancer type 1 susceptibility protein homolog (BRCA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRCA1 Proteins for Pongo pygmaeus (Bornean orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP743602EXP CSB-EP743602EXP CSB-BP743602EXP CSB-MP743602EXP CSB-EP743602EXP-B |
Recombinant Pongo pygmaeus Breast cancer type 1 susceptibility protein homolog (BRCA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRCA1 Proteins for Gorilla gorilla gorilla (Lowland gorilla)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP753729GGZ CSB-EP753729GGZ CSB-BP753729GGZ CSB-MP753729GGZ CSB-EP753729GGZ-B |
Recombinant Gorilla gorilla gorilla Breast cancer type 1 susceptibility protein homolog (BRCA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRCA1 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP769686BO CSB-EP769686BO CSB-BP769686BO CSB-MP769686BO CSB-EP769686BO-B |
Recombinant Bovine Breast cancer type 1 susceptibility protein homolog (BRCA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRCA1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP839156DO CSB-EP839156DO CSB-BP839156DO CSB-MP839156DO CSB-EP839156DO-B |
Recombinant Dog Breast cancer type 1 susceptibility protein homolog (BRCA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRCA1 Proteins for Arabidopsis thaliana (Mouse-ear cress)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP844583DOA CSB-EP844583DOA CSB-BP844583DOA CSB-MP844583DOA CSB-EP844583DOA-B |
Recombinant Arabidopsis thaliana Protein BREAST CANCER SUSCEPTIBILITY 1 homolog (BRCA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRCA1 Proteins for Pan troglodytes (Chimpanzee)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP861936EQV CSB-EP861936EQV CSB-BP861936EQV CSB-MP861936EQV CSB-EP861936EQV-B |
Recombinant Pan troglodytes Breast cancer type 1 susceptibility protein homolog (BRCA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
