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Apoptotic protease-activating factor 1 is a protein in humans that is encoded by APAF1 gene. Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

APAF1 Antibodies

APAF1 for Homo sapiens (Human)

APAF1 Proteins

APAF1 Proteins for Homo sapiens (Human)

APAF1 Proteins for Mus musculus (Mouse)

APAF1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

APAF1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

APAF1 Proteins for Rattus norvegicus (Rat)