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5HT1A

5HT1A,即5-羟色胺1A受体,别名 HTR1A、ADRBRL1、5-HT1A。它是一种G蛋白偶联受体,由人体细胞自身的基因编码,主要在大脑、脊髓、胃肠道等部位表达。5HT1A受体的作用机制涉及与5-羟色胺(5-HT)结合,激活后通过G蛋白信号转导,影响细胞内的cAMP水平,进而调控细胞功能。5HT1A受体在生物学上的意义非常广泛,它参与调节情绪、睡眠、疼痛感知、认知功能等多种生理过程,是抗抑郁药、抗焦虑药等药物研发的重要靶点。异常的5HT1A受体功能与抑郁症、焦虑症、精神分裂症等精神疾病有关,其激动剂或拮抗剂在临床上用于治疗这些疾病。

热销产品

HTR1A Antibody (CSB-PA010881LA01HU)

验证数据

CSB-PA010881LA01HU

Immunohistochemistry analysis of human small intestine tissue using CSB-PA010881LA01HU at dilution of 1:100

CSB-PA010881LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA010881LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

5HT1A Antibodies

5HT1A for Homo sapiens (Human)

5HT1A Proteins

5HT1A Proteins for Homo sapiens (Human)