5HT1A
5HT1A,即5-羟色胺1A受体,别名 HTR1A、ADRBRL1、5-HT1A。它是一种G蛋白偶联受体,由人体细胞自身的基因编码,主要在大脑、脊髓、胃肠道等部位表达。5HT1A受体的作用机制涉及与5-羟色胺(5-HT)结合,激活后通过G蛋白信号转导,影响细胞内的cAMP水平,进而调控细胞功能。5HT1A受体在生物学上的意义非常广泛,它参与调节情绪、睡眠、疼痛感知、认知功能等多种生理过程,是抗抑郁药、抗焦虑药等药物研发的重要靶点。异常的5HT1A受体功能与抑郁症、焦虑症、精神分裂症等精神疾病有关,其激动剂或拮抗剂在临床上用于治疗这些疾病。
热销产品
HTR1A Antibody (CSB-PA010881LA01HU)
验证数据
Immunohistochemistry analysis of human small intestine tissue using CSB-PA010881LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA010881LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
5HT1A Antibodies
5HT1A for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA004142 | HTR1A Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA830794 | HTR1A Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA109594 | HTR1A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA010881LA01HU | HTR1A Antibody | Human | ELISA, IHC, IF |
CSB-PA010881LC01HU | HTR1A Antibody, FITC conjugated | Human | |
CSB-PA010881LD01HU | HTR1A Antibody, Biotin conjugated | Human | ELISA |
5HT1A Proteins
5HT1A Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP010881HU1 CSB-EP010881HU1 CSB-BP010881HU1 CSB-MP010881HU1 CSB-EP010881HU1-B |
Recombinant Human 5-hydroxytryptamine receptor 1A (HTR1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF010881HU | Recombinant Human 5-hydroxytryptamine receptor 1A (HTR1A) | in vitro E.coli expression system |