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  4. Rat anti-Mullerian hormone (AMH) ELISA kit

Rat anti-Mullerian hormone (AMH) ELISA kit

文献引用 (39) 说明书下载
  • 中文名称：
    大鼠缪勒管抑制物质/抗缪勒管激素(AMH)酶联免疫试剂盒
  • 货号：
    CSB-E11162r
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：
CUSABIO Wins 2024 Bioz Rapid Star™ Award in the ELISA category

产品详情

  • 产品描述：
    大鼠缪勒管抑制物质/抗缪勒管激素(AMH)酶联免疫试剂盒（CSB-E11162r）为竞争法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的AMH含量。AMH（抗缪勒管激素）是一种由卵巢和睾丸分泌的激素，对性别分化和生殖系统发育至关重要。其研究机制涉及调节生殖管道发育、抑制原始卵泡募集、影响卵巢储备和生育能力。AMH水平与年龄、卵巢功能和生育状况密切相关。试剂盒检测范围为0.2 ng/mL-15 ng/mL，适用于生殖生物学、内分泌学等领域的科学研究，可用于探索性腺发育机制、评估生殖相关疾病模型中的激素水平动态变化，或用于药物干预实验中对AMH表达调控的效应分析，为深入解析大鼠生殖系统功能提供可靠工具。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
  • 别名：
    Amh ELISA Kit; Muellerian-inhibiting factor ELISA Kit; Anti-Muellerian hormone ELISA Kit; AMH ELISA Kit; Muellerian-inhibiting substance ELISA Kit; MIS ELISA Kit
  • 缩写：
    AMH
  • Uniprot No.：
  • 种属：
    Rattus norvegicus (Rat)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    0.2 ng/mL-15 ng/mL
  • 灵敏度：
    0.1 ng/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Signal Transduction
  • 测定原理：
    quantitative
  • 测定方法：
    Competitive
  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<15%

    Three samples of known concentration were tested twenty times on one plate to assess.

    Inter-assay Precision (Precision between assays): CV%<15%

    Three samples of known concentration were tested in twenty assays to assess.

  • 标准曲线：

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

    ng/ml

    OD1

    OD2

    Average

    0

    2.179

    2.234

    2.207

    0.2

    1.752

    1.667

    1.710

    0.6

    1.411

    1.428

    1.420

    1.75

    0.823

    0.829

    0.826

    5

    0.482

    0.501

    0.491

    15

    0.264

    0.253

    0.259

  • 数据处理：
    ELISA操作视频及标曲绘制软件下载
  • 货期：
    3-5 working days

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Amh Proteins

靶点详情

  • 最新研究进展：
    AMH是一种由生殖细胞产生的生长因子，主要参与了性腺的发育和生殖调节。最新研究表明，AMH在女性中发挥着重要的作用，如参与卵巢生长和发育、卵泡发育和成熟、排卵和孕产等过程。此外，AMH在生殖医学中也被广泛应用于卵巢储备功能评估和IVF治疗等方面。近年来，一些新型AMH检测技术的研究也为AMH在临床上的应用提供了更加准确和可靠的方法。
  • 功能：
    This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
  • 基因功能参考文献：
    1. The study uncovers a new role for AMH in regulating gonadotrope function and suggests that AMH participates in the postnatal elevation of FSH secretion in females. PMID: 27030385
    2. AMH increases GnRH-dependent LH pulsatility and secretion, supporting a central action of AMH on GnRH neurons. PMID: 26753790
    3. Resveratrol reduced antimullerian hormone levels in rat model of polycystic ovary syndrome. PMID: 25667201
    4. AMH is the first hormone/protein shown to have an inhibitory action on primordial follicle assembly. PMID: 21637711
    5. In ovaries from adult cycling rats AMH protein is localized in large primary and secondary follicles and not in primordial or small primary follicles, with its highest expression in the largest preantral follicles. PMID: 20816688
    6. Mullerian inhibiting substance regulates gonadotropin gene expression PMID: 12878721
    7. MIS inhibits regeneration of Leydig cells in ethylene dimethanesulfonate-treated rats by enhancing apoptotic cell death as well as by decreasing proliferative capacity. PMID: 14585814

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    TGF-beta family
  • 数据库链接：

    KEGG: rno:25378

    STRING: 10116.ENSRNOP00000026220

    UniGene: Rn.19121

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