Horse Albumin(Alb) ELISA Kit

    MAU（microalbuminuria）是指尿液中微量白蛋白的异常排出，通常作为肾病的早期标志之一。最新研究表明，MAU与多种疾病相关，包括糖尿病、高血压和心血管疾病等。研究者们正在努力探索MAU与这些疾病之间的关系及其潜在机制，以期为预防和治疗提供更有效的策略。

Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin.

1. the structural homology between HSA and ESA is big, their crystal complexes with Myr-2S-cPA demonstrate significantly different mode of binding of this LPL analogue. HSA binds three molecules of Myr-2S-cPA, whereas ESA only one. Moreover, none of the identified Myr-2S-cPA binding sites overlap in both albumins PMID: 27129297
2. A crystallographic structural study allows identification of serum albumin fragments responsible for immunogenicity and the postulation of a mechanism for equine antigen-antibody recognition. PMID: 22993082

Secreted.

ALB/AFP/VDB family

Plasma.

KEGG: ecb:100034206

STRING: 9796.ENSECAP00000009171

UniGene: Eca.1455