CD40 ligand is a protein in humans that is encoded by CD40LG gene. Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (By similarity).

CD40LG Antibodies

CD40LG for Homo sapiens (Human)

CD40LG Proteins

CD40LG Proteins for Mus musculus (Mouse)

CD40LG Proteins for Homo sapiens (Human)

CD40LG Proteins for Macaca mulatta (Rhesus macaque)

CD40LG Proteins for Felis catus (Cat) (Felis silvestris catus)

CD40LG Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CD40LG Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

CD40LG Proteins for Sus scrofa (Pig)

CD40LG Proteins for Aotus trivirgatus (Night monkey) (Douroucouli)

CD40LG Proteins for Callithrix jacchus (White-tufted-ear marmoset)

CD40LG Proteins for Macaca nemestrina (Pig-tailed macaque)

CD40LG Proteins for Gallus gallus (Chicken)

CD40LG Proteins for Rattus norvegicus (Rat)


CD40LG ELISA Kit for Homo sapiens (Human)

CD40LG ELISA Kit for Mus musculus (Mouse)

CD40LG ELISA Kit for Rattus norvegicus (Rat)