流行SARS-CoV-2变异株产品大合集

浏览次数:295      日期:2021-08-25 16:14:47

2019年底爆发的COVID19疫情仍在全球肆虐。SARS-CoV-2,作为这种流行病的起因,突变速度令人瞠目结舌。SARS-CoV-2仅用了一年多的时间,从 Alpha 发展到 Lambda,让WHO用了将近 1/2 的希腊字母来为其变异株命名。2020年12月末,在英国发现SARS-CoV-2变异株Alpha,至此,英国疫情失控。紧接着,在南非发现了变异株Beta,在印度发现了变异株Delta,在秘鲁发现了变异株Lambda。

针对全球SARS-CoV-2的主要变种,华美生物可提供多种标签的优质突变抗原。绝大多数突变抗原已验证生物活性。

如果您对其他突变株感兴趣,可点击页面右侧的在线咨询联系我们定制。➤➤➤

>>SARS-CoV-2 Lambda | C.37 (南美突变株)

Target Product Name Code Source Mutation Tag Info
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (R203K,G204R) (Active) CSB-EP3325GMY(M12) E.coli R203K, G204R N-terminal 6xHis-tagged

>>SARS-CoV-2 Delta | B.1.617.2 (印度突变株)

Target Product Name Code Source Mutation Tag Info
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (D63G,R203M,D377Y) (Active) CSB-EP3325GMY(M14) E.coli D63G, R203M, D377Y N-terminal 6xHis-tagged

>>SARS-CoV-2 Kappa | B.1.617.1 (印度突变株)

Target Product Name Code Source Mutation Tag Info
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (R203M,D377Y) (Active) CSB-EP3325GMY(M13) E.coli R203M, D377Y N-terminal 6xHis-tagged

>>SARS-CoV-2 Alpha | B.1.1.7 (英国突变株)

Target Product Name Code Source Mutation Tag Info
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (D3L,R203K,G204R,S235F) (Active) CSB-EP3325GMY(M1) E.coli D3L, R203K, G204R, S235F N-terminal 6xHis-tagged
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (R203K,G204R) (Active) CSB-EP3325GMY(M12) E.coli R203K, G204R N-terminal 6xHis-tagged
S1 Recombinant Human Novel Coronavirus Spike glycoprotein (S) (D614G),partial (Active) CSB-MP3324GMY(M1) Mammalian cell D614G C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (N501Y),partial (Active) CSB-MP3324GMY1(M6) Mammalian cell N501Y C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (N501Y),partial (Active) CSB-MP3324GMY1(M6)k2 Mammalian cell N501Y C-terminal 6xHis-mFC-tagged

>>SARS-CoV-2 Beta | B.1.351 (南非突变株)

Target Product Name Code Source Mutation Tag Info
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (T205I) (Active) CSB-EP3325GMY(M2) E.coli T205I N-terminal 6xHis-tagged
S1 Recombinant Human Novel Coronavirus Spike glycoprotein (S) (D614G), partial (Active) CSB-MP3324GMY(M1) Mammalian cell D614G C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (N501Y), partial (Active) CSB-MP3324GMY1(M6) Mammalian cell N501Y C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (N501Y), partial (Active) CSB-MP3324GMY1(M6)k2 Mammalian cell N501Y C-terminal 6xHis-mFC-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (K417N), partial CSB-MP3324GMY1(M7) Mammalian cell K417N C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (K417N), partial CSB-MP3324GMY1(M7)h8 Mammalian cell K417N C-terminal mFC-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (E484K), partial CSB-MP3324GMY1(M8) Mammalian cell E484K C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (E484K), partial (Active) CSB-MP3324GMY1(M8)h8 Mammalian cell E484K C-terminal mFC-tagged

>>SARS-CoV-2 Gamma | P.1 (巴西突变株)

Target Product Name Code Source Mutation Tag Info
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (P80R) (Active) CSB-EP3325GMY(M3) E.coli P80R N-terminal 6xHis-tagged
S1 Recombinant Human Novel Coronavirus Spike glycoprotein (S) (D614G),partial (Active) CSB-MP3324GMY(M1) Mammalian cell D614G C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (N501Y),partial (Active) CSB-MP3324GMY1(M6) Mammalian cell N501Y C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (N501Y),partial (Active) CSB-MP3324GMY1(M6)k2 Mammalian cell N501Y C-terminal 6xHis-mFC-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein(S)(E484K),partial CSB-MP3324GMY1(M8) Mammalian cell E484K C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein(S) (E484K), partial (Active) CSB-MP3324GMY1(M8)h8 Mammalian cell E484K C-terminal mFC-tagged

>>其他SARS-CoV-2 突变株

Target Product Name Code Source Mutation Tag Info
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (P13L) (Active) CSB-EP3325GMY(M4) E.coli P13L N-terminal 6xHis-tagged
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (D103Y) (Active) CSB-EP3325GMY(M5) E.coli D103Y N-terminal 6xHis-tagged
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (L230F) (Active) CSB-EP3325GMY(M9) E.coli L230F N-terminal 6xHis-tagged
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (I292T) (Active) CSB-EP3325GMY(M10) E.coli I292T N-terminal 6xHis-tagged
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (Q384H) (Active) CSB-EP3325GMY(M11) E.coli Q384H N-terminal 6xHis-tagged
N Recombinant Human Novel Coronavirus Nucleoprotein (N) (S202N) (Active) CSB-EP3325GMY(M8) E.coli S202N N-terminal 6xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (V367F),partial (Active) CSB-MP3324GMY1(M1) Mammalian cell V367F C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (W436R), partial (Active) CSB-MP3324GMY1(M2) Mammalian cell W436R C-terminal 10xHis-tagged
S1-RBD Recombinant Human Novel Coronavirus Spike glycoprotein (S) (G476S), partial (Active) CSB-MP3324GMY1(M4) Mammalian cell G476S C-terminal 10xHis-tagged

>>部分验证数据

● Recombinant Human Novel Coronavirus Nucleoprotein (N)(R203K,G204R) (Active) (CSB-EP3325GMY(M12))

Its purity is greater than 96% as determined by SDS-PAGE.
Its binding ability measured by functional ELISA with N Mouse Monoclonal Antibody at 2 μg/ml, of which EC50 is 6.775-13.04 ng/ml.
Its binding ability measured by functional ELISA with N Recombinant Antibody at 2 μg/ml, of which EC50 is 4.664-8.256 ng/ml.

● Recombinant Human Novel Coronavirus Nucleoprotein (N)(D63G,R203M,D377Y) (Active) (CSB-EP3325GMY(M14))

Its purity is greater than 85.7% as determined by SDS-PAGE.
Its binding ability measured by functional ELISA with N Mouse Monoclonal Antibody at 2 μg/ml, of which EC50 is 3.834 - 5.294 ng/ml.
Its binding ability measured by functional ELISA with N Recombinant Antibody at 2 μg/ml, of which EC50 is 1.304 - 1.875 ng/ml ng/ml.

● Recombinant Human Novel Coronavirus Spike glycoprotein(S) (E484K), partial (Active) (CSB-MP3324GMY1(M8)h8)

Its purity is greater than 90% as determined by SDS-PAGE.
Its binding ability measured by functional ELISA with human ACE2 at 2 μg/ml, the EC50 is 6.597-8.187 ng/ml.
Its binding ability measured by functional ELISA with Biotin-S Antibody at 2 μg/ml, the EC50 is 118.7 ng/ml.