蛋白 > 重组蛋白 > Recombinant Mouse Calreticulin(Calr)
  • 产品类型:
    Recombinant Protein
  • 产品名称:

    Recombinant Mouse Calreticulin(Calr) IN STOCK

  • 货期:
    3-7 工作日
  • uniprot号:
    P14211
  • 货号:
    CSB-YP004458MO
  • 规格:
    ¥9558
  • 蛋白名称:
    Recommended name: CalreticulinAlternative name(s): CRP55 Calregulin Endoplasmic reticulum resident protein 60 Short name= ERp60 HACBP
  • 基因名称:
    Calr
  • 别名:
    CalrCalreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP
  • 种属:
    Mus musculus (Mouse)
  • 蛋白描述:
    Full Length of Mature Protein
  • 简介:
    Calcium-binding chaperone that promotes folding, oligomeric assbly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis .
  • 分子量:
    48.3kDa
  • 蛋白标签:
  • 蛋白来源:
    Yeast
  • 蛋白纯度:
    Greater than 90% as determined by SDS-PAGE.
  • 蛋白图:

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP004458MO could indicate that this peptide derived from Yeast-expressed Mus musculus (Mouse) Calr.

    Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP004458MO could indicate that this peptide derived from Yeast-expressed Mus musculus (Mouse) Calr.

  • 缓冲液:
    Tris-based buffer,50% glycerol
  • 蛋白储存:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 使用注意:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 参考文献:
    Structural and functional relationships between the lectin and arm domains of calreticulin.Pocanschi C.L., Kozlov G., Brockmeier U., Brockmeier A., Williams D.B., Gehring K.J. Biol. Chem. 286:27266-27277(2011)
  • 说明书:

    注:产品说明书可能有改进,请直接与CUSABIO产品专员联系,索取最新版说明书!

  • 氨基酸序列:
    DPAIYFKEQFLDGDAWTNRWVESKHKSDFGKFVLSSGKFYGDLEKDKGLQTSQDARFYALSAKFEPFSNK
    GQTLVVQFTVKHEQNIDCGGGYVKLFPSGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLI
    NKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDD
    PTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNP
    EYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRL
    KEEEEDKKRKEEEEAEDKEDDDDRDEDEDEEDEKEEDEEESPGQAKDEL
  • 表达区域:
    18-416aa
  • 研究领域:
    Others
  • 引用文献:
    1. Calreticulin Blockade Attenuates Murine Acute Lung Injury by Inducing Polarization of M2 Subtype Macrophages , Z Jiang,Front Immunol,2020