蛋白 > 重组蛋白 > Recombinant Human Histone PARylation factor 1(HPF1)
  • 产品类型:
    Recombinant Protein
  • 产品名称:

    Recombinant Human Histone PARylation factor 1(HPF1) IN STOCK

  • 货期:
    3-7 工作日
  • uniprot号:
    Q9NWY4
  • 货号:
    CSB-EP865162HU
  • 规格:
    ¥14796
  • 蛋白名称:
    C4orf27
  • 基因名称:
    HPF1
  • 别名:
    C4orf27; CD027_HUMAN; chromosome 4 open reading frame 27; FLJ20534; FLJ33423; FLJ42042; UPF0609 protein C4orf27
  • 种属:
    Homo sapiens (Human)
  • 蛋白描述:
    Full Length
  • 简介:
    Acts as a cofactor for serine ADP-ribosylation by conferring serine specificity on PARP1 and PARP2: interacts with PARP1 and PARP1 and is able to change amino acid specificity toward serine. Promotes histone serine ADP-ribosylation in response to DNA damage, limiting DNA damage-induced PARP1 hyper-automodification, and ensuring genome stability
  • 分子量:
    59.4 kDa
  • 蛋白标签:
  • 蛋白来源:
    E.coli
  • 蛋白纯度:
    Greater than 85% as determined by SDS-PAGE.
  • 蛋白图:

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP865162HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) C4orf27.

    Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP865162HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) C4orf27.

  • 缓冲液:
    Tris-based buffer,50% glycerol
  • 蛋白储存:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 使用注意:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 参考文献:
    "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
    Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., Ottenwaelder B., Obermaier B. Poustka A.
    Genome Res. 11:422-435(2001)
  • 说明书:

    注:产品说明书可能有改进,请直接与CUSABIO产品专员联系,索取最新版说明书!

  • 氨基酸序列:
    MVGGGGKRRPGGEGPQCEKTTDVKKSKFCEADVSSDLRKEVENHYKLSLPEDFYHFWKFCEELDPEKPSD
    SLSASLGLQLVGPYDILAGKHKTKKKSTGLNFNLHWRFYYDPPEFQTIIIGDNKTQYHMGYFRDSPDEFP
    VYVGINEAKKNCIIVPNGDNVFAAVKLFLTKKLREITDKKKINLLKNIDEKLTEAARELGYSLEQRTVKM
    KQRDKKVVTKTFHGAGLVVPVDKNDVGYRELPETDADLKRICKTIVEAASDEERLKAFAPIQEMMTFVQF
    ANDECDYGMGLELGMDLFCYGSHYFHKVAGQLLPLAYNLLKRNLFAEIIEEHLANRSQENIDQLAA
  • 表达区域:
    1-346aa
  • 研究领域:
    others
  • 引用文献:
    1. Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans , Cho CC, et al,NATURE COMMUNICATIONS,2019