Recombinant Dog Caspase-1(CASP1)

  • 货号:
    CSB-YP882005DO
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 货号:
    CSB-EP882005DO
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 货号:
    CSB-EP882005DO-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 货号:
    CSB-BP882005DO
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 货号:
    CSB-MP882005DO
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    CASP1
  • Uniprot No.:
  • 别名:
    CASP1; IL1BCCaspase-1; CASP-1; EC 3.4.22.36; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
  • 种属:
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白长度:
    Full Length of Mature Protein
  • 表达区域:
    120-297
  • 氨基酸序列
    G PTIPDSEEST DTLKLCPPET FVKMYKEKAE EIYPIKERKD RTRLALIICN IEFDHLSTRD GAELDIAGME SLLEGLGYSV VVKRKLTAKG MESVLREFAA RPEHKSSDST FLVLMSHGIL NGICGTAHSV ENPDVLAYDT IFQIFNNRHC LNLKDKPKVI IIQACRGENP GELWVSD
  • 蛋白标签:
    The following tags are available.
    N-terminal His-tagged
    Tag-Free
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

靶点详情

  • 功能:
    Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive.
  • 亚细胞定位:
    Cytoplasm
  • 蛋白家族:
    Peptidase C14A family
  • 数据库链接: