Recombinant Human Fibroblast growth factor 17 protein(FGF17)

In Stock
  • 货号:
    CSB-AP002451HU
  • 规格:
    ¥15702
  • 图片:
  • 其他:

产品详情

  • 纯度:
    >95% as determined by SDS-PAGE and HPLC.
  • 内毒素:
    Less than 1.0 EU/μg as determined by LAL method.
  • 生物活性:
    Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 10 ng/ml, corresponding to a specific activity of >1.0x105 IU/mg.
  • 基因名:
    FGF17
  • Uniprot No.:
  • 别名:
    FGF 13; FGF 17; FGF-17; FGF13; Fgf17; FGF17_HUMAN; Fibroblast growth factor 17; HH20
  • 种属:
    Homo sapiens (Human)
  • 蛋白长度:
    Full Length of Mature Protein
  • 来源:
    E.Coli
  • 分子量:
    22.6 kDa
  • 表达区域:
    23-216aa
  • 氨基酸序列
    M+TQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT
  • 蛋白标签:
    Tag-Free
  • 产品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液:
    0.2 μm filtered PBS, pH 7.4 ,lyophilized
  • 储存条件:
    Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    5-10 business days
  • Datasheet & COA:
    Please contact us to get it.

靶点详情

  • 功能:
    Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.
  • 基因功能参考文献:
    1. FGF17 and IL17RD prpopsed as the two top candidates in the entire proteome on the basis of a statistical test of their protein-protein interaction patterns to proteins known to be altered in congenital hypogonadotropic hypogonadism. PMID: 23643382
    2. FGF17 expression is increased 2-fold in benign prostatic hyperplasia and may contribute to the increased epithelial proliferation seen in this disease. PMID: 15129425
  • 相关疾病:
    Hypogonadotropic hypogonadism 20 with or without anosmia (HH20)
  • 亚细胞定位:
    Secreted
  • 蛋白家族:
    Heparin-binding growth factors family
  • 组织特异性:
    Preferentially expressed in the embryonic brain.
  • 数据库链接:

    HGNC: 3673

    OMIM: 603725

    KEGG: hsa:8822

    STRING: 9606.ENSP00000352414

    UniGene: Hs.248192